Many clients feel refreshed and mentally stimulated immediately after the first treatment, due to the release of endorphins. This uplifted mood may last anywhere from a few hours to a few days. Depending on the person and condition, there may be immediate pain relief for joints and muscles, improved energy, and increased flexibility. Metabolism can be boosted for up to 48 hours, however, weight loss and changes in skin texture or reduction in cellulite will take a longer series of treatments.